The Autumn 2025 edition of O&G Magazine explores the complexities of early pregnancy—a period of hope and anticipation, but also uncertainty and profound loss for many. This issue discusses the management of complications such as caesarean scar pregnancy, tubal ectopic pregnancy, and threatened miscarriage, and examines the latest research into progesterone's role in improving pregnancy outcomes. It features personal insights from advocates like Samantha Payne of the Pink Elephants Support Network, and Isabelle Oderberg of the Early Pregnancy Loss Coalition, highlighting the importance of compassionate, patient-centred care, empowering clinicians to better support patients throughout this critical time.